WAO 2010 International Scientific Conference Online Resource Center

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Update on Asthma Research and Clinical Practice

Learning Objectives:

  • To define asthma exacerbations and their relevance to future risk and impairment
  • To explain the concept of asthma "control"
  • To review various approaches for the recognition and treatment of difficult-to-control asthma

Asthma control: Setting goals
Eric Bateman

Learning Objectives:

  • To review current thinking on what defines acceptable asthma control
  • To review tools that are available to evaluate control
  • To review how to set goals to achieve asthma control

Difficult-to-control asthma
Paul O'Byrne

Learning Objectives:

  • To define "difficult-to-control asthma"
  • To describe populations that may be at particular risk
  • To review the natural history of difficult-to-control asthma

Asthma exacerbation and reducing emergency room visits
Tari Haahtela

Learning Objectives:

  • To review what constitutes an asthma exacerbation
  • To describe common factors that trigger asthma exacerbations both in children and adults
  • To explain how prevention of exacerbations may reduce loss of lung function over time


Asthma and Co-morbidities

Learning Objectives:

  • To review co-morbid conditions that may manifest as asthma
  • To address the relationship between systemic disorders and asthma and its treatment
  • To describe diagnostic implications

Asthma and rheumatic disorders and vasculitis
Lanny Rosenwasser

Learning Objectives:

  • To provide an understanding of other immunological conditions that manifest as asthma
  • To show when to be suspicious of systemic causes
  • To explain the relationship between the management of connective tissue and vasculitic disorders

Asthma and osteoporosis and osteopenia
Dennis Ledford

Learning Objectives:

  • To review factors influencing bone density in allergic disease and naturally
  • To identify the factors involved in inhaled corticosteroids and growth in children and osteoporosis in adults
  • To discuss management of bone disorders in asthma and allied disorders

Asthma in the elite athlete
Sergio Bonini

Learning Objectives:

  • To learn how to assess allergic disease in athletes and its impact on sporting activity
  • To review implications of EIA in competitive sports individuals
  • To discuss the prevention and management of allergic disease in athletes


Asthma and Upper Airway Co-morbidities: Research and Clinical Practice Updates

Asthma, rhinosinusitis and otitis media with effusion
Ruby Pawankar

Learning Objectives:

  • To provide knowledge of different types of disorders and underlying mechanisms
  • To review the impact of co-morbidity
  • To review approaches to the management of these disorders

Practical aspects of managing asthma and rhinosinusitis in the clinic
Michael A. Kaliner

Learning Objectives:

  • To emphasize the importance of obtaining a clear diagnosis
  • To review the approaches to therapy including for severe disease

Asthma and nasal polyps
Hae-Sim Park

Learning Objectives:

  • To explain the mechanisms of polyp formation including pathology and risk factors
  • To review the diagnosis of nasal polyposis
  • To review treatment options and prevention of recurrence

Asthma and aspirin sensitivity
Marek L. Kowalski

Learning Objectives:

  • To explain the proposed mechanisms of aspirin-intolerant asthma
  • To explain how to diagnose aspirin-intolerant asthma
  • To review the management of aspirin-intolerant asthma


Asthma in the Elderly

Asthma and co-morbidities in the elderly
Neil Barnes

Learning Objectives:

  • To recognize the importance and high prevalence of asthma in the elderly
  • To consider clinical presentations of asthma and common co-morbidities such as, heart failure, diabetes, hypertension, GERD, and ways of assessing their relative contributions

Life-long asthma and its relationship to COPD
Stephen T. Holgate

Learning Objectives:

  • To review the effects of life-long asthma in the elderly and how it differs from COPD
  • To explore methods for distinguishing asthma from COPD, clinically and in the laboratory

Overcoming gaps and optimizing management of asthma in the elderly
Louis-Philippe Boulet

Learning Objectives:

  • To consider challenges in treating asthma in the elderly and ways of overcoming these challenges
  • To review the goals for asthma management and monitoring of outcomes in the elderly
  • To consider the problems of drug interactions in the elderly


Middle East Asia Allergy, Asthma and Immunology Congress Symposium:
Asthma and Upper Airway Co-morbidities in the Gulf and Near East

Genetics of asthma
Saleh Al-Muhsen

Learning Objective:

  • To provide an understanding of the regional characteristics of the genetics, clinical phenotypes and therapeutic responses of asthma and co-morbid allergies

Triggers of childhood asthma
Zeina Baz

Learning Objective:

  • To provide an understanding of the regional triggers and risk factors of childhood asthma

Asthma and rhinitis
Mona Al-Ahmad

Learning Objective:

  • To review the epidemiology, risk factors of asthma and co-morbid allergic rhinitis

Asthma and sleep disorders
Ashraf Al Zaaibi

Learning Objective:

  • To review the relationship between asthma and obstructive sleep apnea in the region and the management strategies


Asthma and Upper Airway Co-morbidities: Looking Ahead

Asthma and vocal cord dysfunction
Dennis Ledford

Learning Objective:

  • To review functional upper airway disorders, their mechanisms, relationship with asthma, diagnosis and management

Asthma, GERD and laryngeal pharyngeal reflux (LPR)
Richard F. Lockey

Learning Objectives:

  • To review the epidemiology of GERD and its relationship with asthma
  • To explain the mechanisms underlying GERD and LPR in the asthmatic
  • To show how to investigate for GERD and LPR in the asthmatics: Who, when and how?
  • To review treatment for GERD and LPR in asthma and outcomes

Asthma and obstructive sleep apnea (OSA)
Fulvio Braido

Learning Objectives:

  • To explore the relationship between asthma and OSA
  • To review disturbed sleep in asthma and approaches to its management


An Overview of Pediatric Asthma

Wheezing pre-asthma phenotypes in pre-school children
Robert Lemanske

Learning Objectives:

  • To describe the various wheezing phenotypes and their relationship to asthma expression in later childhood
  • To explain what factors are most influential in early life that predict asthma risk in school-aged children
  • To consider the contribution of both genetic and environmental factors to childhood asthma

Asthma and allergies in school-age children and adolescents
Carlos E. Baena-Cagnani

Learning Objectives:

  • To define the terms "atopic" and "allergic sensitization"
  • To review at what age immediate hypersensitivity testing can be performed and interpreted
  • To explain the contribution of aeroallergens to asthma pathogenesis

Prevention of pediatric asthma and allergies
Tari Haahtela

Learning Objectives:

  • To review strategies for the prevention of allergic sensitization
  • To discuss issues related to the use of probiotics
  • To address what factors may be relevant to the prevention of asthma


Asthma, Endocrine Disorders and Iatrogenesis

Asthma treatment and the HPA axis
Paul Greenberger

Learning Objectives:

  • To review HPA axis suppression and its clinical significance in adults and children
  • To describe methods for diagnosing HPA axis suppression
  • To explain the implication on selection of treatment for asthma and allergic diseases

Asthma and endocrine disorders
Dennis Ledford

Learning Objectives:

  • To describe associations between diabetes, obesity and asthma, and the special considerations in their management
  • To describe associations between thyrotoxicosis and asthma and implications for treatment

Asthma co-morbidities in pregnancy
Sandra González-Díaz

Learning Objectives:

  • To provide an update on the relationship between asthma and pregnancy
  • To review the management of asthma during pregnancy with special emphasis on safety of treatment


New Concepts in Severe Asthma

Asthma phenotypes: A clinically useful concept
Adnan Custovic

Learning Objective:

  • To consider the potential of an understanding of phenotyping upon the design of new treatments and new strategies in asthma management

Defining and diagnosing severe asthma
Eric Bateman

Learning Objective:

  • To review new definitions of severe asthma (WHO; ERS/ATS Task Force on Severity and Control) and their clinical implications for the practitioner

Small airways disease in asthma
WAO Small Airways Diseases Working Group Lecture

Stephen Peters

Learning Objectives:

  • To define small airway function in asthma
  • To review pathophysiological alterations that are unique to small airway
  • To assess therapies that are targeted to the small airway


Sanofi-Aventis Symposium - Allergic Airways Diseases: From the Evidence to Clinical Practice

Burden of allergic diseases in Middle East countries
Faheem Tadros

Learning Objective:

  • To highlight the increase of allergic rhinitis and comorbidities and their impact on the burden of disease in the Middle East region

From clinical evidence to real practice
Carlos E. Baena-Cagnani

Learning Objectives:

  • To increase knowledge and awareness of current, evidence-based best practices in allergic rhinitis and co-morbidities
  • To learn how to turn management practices into routine clinical practice

Allergic airways diseases: Evidence-based medicine
G. Walter Canonica

Learning Objective:

  • To outline the clinical evidence of available medications for the management of allergic rhinitis (fexofenadine)


Immunotherapy and Immune Modulators in Asthma and Allergic Rhinitis

Subcutaneous immunotherapy
Harold Nelson

Learning Objectives:

  • To review subcutaneous immunotherapy techniques and their risks and benefits
  • To identify immune mechanisms related to benefits derived from immunotherapy
  • To review data that suggests that immunotherapy in early life may alter asthma expression and severity

Sublingual immunotherapy for patients with allergic rhinitis and asthma
G. Walter Canonica

Learning Objectives:

  • To review the technique of sublingual immunotherapy for types and doses of allergens administered
  • To explain the risks and the benefits of sublingual immunotherapy
  • To identify patient populations that would be appropriate targets for this type of therapy

Novel strategies and future directions in immunotherapy
Glenis Scadding

Learning Objectives:

  • To address how to improve the effectiveness and safety of immunotherapy
  • To review new therapeutic entities in trial
  • To consider the implications of immunotherapy for the allergic march in children


European Academy of Allergy and Clinical Immunology Symposium:
The Multiple Faces of Asthma

The three dimensions of asthma: Asthma type, asthma severity and asthma personality
Jan Lötvall

Learning Objectives:

  • To discuss the concept of asthma being a syndrome consisting of several subgroups of disease each expressing separate phenotypic characteristics
  • To give examples of subgroups that may have distinct pathophysiological mechanisms
  • To present factors that are related to severity of asthma regardless of subgroup

Immunological mechanisms of asthma phenotypes
J. Christian Virchow

Learning Objectives:

  • To review the role of various immune and inflammatory cells in asthma phenotypes
  • To discuss immunological mechanisms that have helped to increase understanding of the cellular and molecular mechanisms of asthma

Environmental influences on asthma and allergy phenotypes
Ömer Kalayci

Learning Objectives:

  • To understand the basic mechanisms underlying the complex genetic diseases
  • To define gene-environment interaction
  • To identify the specific gene-environment interactions that are relevant in allergic diseases and asthma
  • To explain the effect of smoke exposure that is modulated by the genetic variants
  • To show how genes explain the diverse effects of endotoxin exposure in humans


Asthma and COPD

Biomarkers in the assessment of asthma and COPD
Louis-Philippe Boulet

Learning Objectives:

  • To provide insight into how disordered cell and molecular processes in these diseases can be used as diagnostic and prognostic tests
  • To offer new knowledge about methods used to find biomarkers related to disease mechanisms
  • To provide examples of biomarkers that influence the stratification of these diseases

Diagnosing and managing asthma and COPD
Neil Barnes

Learning Objectives:

  • To provide updates on new methods that help in diagnosis of lung diseases
  • To show how treatments for these conditions can be tailored to individual patient needs
  • To explain about the control of underlying disease processes and exacerbations

Smoking cessation
Riccardo Polosa

Learning Objectives:

  • To explain how active and passive smoke exposure influences asthma and COPD
  • To provide insight into different ways that people can be encouraged to quit smoking
  • To identify how best to maintain non-smoking in a previously habitual smoker

Allergen avoidance strategies to reduce morbidity in asthma
Adnan Custovic

Learning Objectives:

  • To review allergen avoidance strategies: Those that work and those that do not
  • To review avoidance of drugs and selected domestic and occupational triggers
  • To describe unusual forms of asthma
  • To consider the role of vaccination against influenza and other specific and non-specific antibacterial measures


Asthma and Ocular Allergy Co-morbidity

Epidemiology and pathomechanisms of ocular allergy
Michael S. Blaiss

Learning Objectives:

  • To describe the cellular, mediator and cytokine mechanisms of both acute and chronic allergic eye disease
  • To explain how to connect mechanisms to prognosis and treatment

Asthma and rhinoconjunctivitis co-morbidity and quality-of-life
Fulvio Braido

Learning Objectives:

  • To explain how allergic conjunctivitis can impact not only symptoms of asthma but also quality-of-life measures
  • To review the concept of the upper and lower airways expressing allergic responses together

Treating the ocular component of allergic rhinoconjunctivitis
Sergio Bonini

Learning Objectives:

  • To describe the treatment options, with guidelines for their use, of this condition in its various stages of severity and chronicity
  • To explain in detail the "United Airways" concept


Asthma and Viral Infections

Early viral infections: Their role in the development of asthma
Robert Lemanske

Learning Objectives:

  • To review the contribution of viral respiratory tract infections to pre-school wheezing
  • To explain the role of rhinovirus infections in asthma risk
  • To compare and contrast RS V versus rhinovirus infections in early childhood and their impact on the development of childhood asthma

Managing the wheezing infant
Alessandro Fiocchi

Learning Objectives:

  • To describe the various wheezing phenotypes
  • To review information regarding how to identify the likelihood of asthma developing in children who wheeze early in life
  • To present data regarding whether early recognition and treatment of pre-school wheezing can prevent the development of asthma

Non-viral triggers of asthma exacerbation
Louis-Philippe Boulet

Learning Objectives:

  • To review the factors that trigger exacerbations of asthma in addition to viruses
  • To present data as to the relative importance of various non viral triggering factors in disease management (both prevention and intervention)
  • To consider whether various triggering mechanisms induce different pathophysiologic changes


Asthma and Chest Co-morbidities in the Middle East

Asthma management strategies in the Middle East
Majdi Idrees

Learning Objective:

  • To review asthma management strategies in the region

The impact of olive pollens on allergy and asthma in Jordan
Hani Ababneh

Learning Objective:

  • To discuss how the stopping of culturing olive trees inside the city increases the allergy, especially in children
  • To review how olive pollens during pollinosis (May to June) trigger asthmatic attacks in allergic and asthmatic patients and to explain why these patients should avoid exposure to these pollens during pollinosis

Monoclonal antibodies in asthma therapy - Middle East perspective
Yehia El-Gamal

Learning Objective:

  • To review the role of monoclonal antibodies in asthma management in the region


Asthma and Concomitant Chest Diseases

Occupational rhinitis and asthma
Hae-Sim Park

Learning Objectives:

  • To consider guidelines for the diagnosis and management of occupational asthma and rhinitis
  • To provide a discussion on the mechanisms of the disease

Asthma, cystic fibrosis and bronchiectasis
Neil Barnes

Learning Objectives:

  • To review the role of allergy in cystic fibrosis and bronchiectasis and the development of asthma
  • To consider the role of allergy and asthma in the pathogenesis of bronchiectasis including bronchopulmonary aspergillosis

Cough variant asthma
Pramod Kelkar

Learning Objectives:

  • To explain cough as a symptom of asthma
  • To show how to recognize the entity of cough variant asthma and consider approaches to its diagnosis and management


Hereditary Angioedema (HAE): Spotlight on the Latest Advances in Diagnosis and Treatment

Clinical presentation and differential diagnosis
Timothy J. Craig

Learning Objectives:

  • To be able to appreciate the effect HAE has on patients with this disorder
  • To be able to recognize and diagnose the HAE
  • To improve patient care and outcomes

Treatment options for HAE
Konrad Bork

Learning Objectives:

  • To recognize the symptoms of hereditary angioedema due to C1 inhibitor deficiency
  • To identify to goals of treatment
  • To highlight the treatment options for acute attacks and long-term prophylaxis