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World Allergy Organization
WAO's mission: To be a global resource and advocate in the field of allergy, advancing excellence in clinical care through education, research and training as a world-wide alliance of allergy and clinical immunology societies.

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WAO Medical Book Review

Posted: January 2011

Anaphylaxis (Chemical Immunology and Allergy, Volume 95)
Edited by Johannes Ring
2010 S. Karger AG
ISBN: 978-3-8055-9441-7

List Price: Print Edition $198
Available from: Karger

Reviewer:
Ahmed Butt, MD
Division of Allergy and Clinical Immunology
Department of Internal Medicine
University of South Florida
James A. Haley Veterans' Hospital
Tampa, Florida USA

Description
This book provides an in-depth review on anaphylaxis pertinent to any clinician whatever their specialty. A thorough review of this subject is presented in a concise format, emphasizing the pathophysiology of anaphylaxis as it translates into clinical medicine.

Purpose
The goal of the text is to provide a high yield review on the epidemiology, pathophysiology, and diagnostic and clinical manifestations of anaphylaxis. The incorporation of breakthrough research performed by experts worldwide enables the reader to better understand the etiology of clinical manifestations and current treatment modalities. This book is designed to educate not only allergists and immunologists but also physicians from any discipline and even lay individuals.

Audience
The reference will be a benefit to any professional, novice or experienced, in various medical disciplines. Although it better serves medical professionals, it is written with clarity.

Features
There are five major sections in this text. The first three focus on the background of anaphylaxis, i.e., epidemiology, pathophysiology, clinical symptomatology and diagnosis. The fourth is devoted to specific allergens and elicitors of anaphylaxis. Included in this section is a description of the pathophysiology, clinical presentation and management of reactions to venoms, radiocontrast media, analgesics and anesthetics. Finally, the last section discusses the treatment and management of anaphylaxis in a concise, yet comprehensive manner.

Each section incorporates significant breakthroughs on anaphylaxis quoting reputable journals from throughout the world permitting the reader to appreciate the complexity in defining and managing this life-threatening condition. Limitations within various studies are acknowledged enabling the reader to interpret their significance more accurately.

Assessment
The book provides a thorough overview of anaphylaxis. It is a concise, to the point review, which helps keep the reader's attention. Sections of the text are comprehensible to all educated individuals, yet contain information pertinent to the specialists who regularly manage and treat anaphylaxis. The cellular and molecular pathophysiology is adequately reviewed and therefore, may be a useful reference for those interested in understanding the basic science of anaphylaxis. I recommend this text to physicians and other medical professionals primarily because it explains the rationale for current guidelines used to treat and manage anaphylaxis through evidence based medicine.