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WAO Medical Book Review

Posted: November 2012

Pathogenesis and Management of Atopic Dermatitis
(Current Problems in Dermatology, Volume 41)
Edited by Tetsuo Shiohara
2011 Karger
ISBN: 978-3-8055-9686-2
e-ISBN: 978-3-8055-9687-9

List Price: $220 USD
Available from: Karger

Esmeralda Shehu, MD
Clinic of Allergy and Clinical Immunology
Durres Hospital

Pathogenesis and Management of Atopic Dermatitis is an indispensable, handy book written in a caring style. The author makes a strong point: understanding and clarifying the enigmas in the pathogenesis of atopic dermatitis (AD) will lead us in successful management of the disease. A notable feature of this book is its comprehensive and systematic coverage of pathogenic mechanisms and systematic treatments of AD.

This book provides the reader with detailed information about the pathogenic mechanism and the treatment of atopic dermatitis.

This book can be most helpful for allergists and clinical immunologists, dermatologists and pediatricians. Medical students, residents and fellows may find this book useful for exam study.

Pathogenesis and Management of Atopic Dermatitis book has 13 chapters that describe the pathogenesis and treatment of atopic dermatitis. The author has included figures to illustrate the text, tables and anatomopathological views. For example, one can read all the essential information about the evidence for the role of the hygiene hypothesis in atopic dermatitis and a quick description of filaggrin gene mutations that demonstrate that this is not the only gene responsible for AD. The other parts consist of a detailed exposition of the antimicrobial skin barrier, the role of innate and adaptive immunity, the defective sweating and all the cytokines and chemokines involved in pathogenic mechanism of AD. It gives information on classifying the severity of AD by referring to SCORAD index. The last chapter provides an interesting discussion of the different kinds of systemic therapies for AD.

This is an excellent book that provides comprehensive information about AD from pathophysiology to diagnosis to approach to therapy. I used this book during my training, and I can recommend it to other allergists/immunologists at all levels of training and career.