Medical Journal Reviews
1. Drug desensitization to chemotherapeutic agents and monoclonal antibodies.
Hong DI, Dioun AF. Indications, protocols, and outcomes of drug desensitizations for chemotherapy and monoclonal antibodies in adults and children. The Journal of Allergy and Clinical Immunology: In Practice 2014; 2(1): 13-19. (doi:10.1016/j.jaip.2013.11.007)
Editor’s comment: The authors reviewed the steps involved in the evaluation of hypersensitivity reactions to chemotherapeutic agents and monoclonal antibodies. They discussed the factors to consider before making a decision to desensitize, the implementation of desensitization protocols, and the outcomes of such procedures.
2. Occupational asthma is potentially preventable in most cases.
Tarlo SM and Lemiere C. Occupational asthma. The New England Journal of Medicine 2014; 370: 640-649. (doi:10.1056/NEJMra1301758)
Editor’s comment: This review focuses on current data about occupational asthma, defined as asthma due to conditions attributable to work exposures and not to causes outside the workplace.
3. Improving the health of our patients with severe asthma.
Fan Chung K, Wenzel SE, Brozek JL, Bush A, Castro M et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. European Respiratory Journal 2013; published online before print, 12 December. (doi:10.1183/09031936.00202013)
Editor’s comment: Supported by the American Thoracic Society and the European Respiratory Society, a task force reviewed the definition and provided recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults.
4. Diagnosis of drug and narcotic allergy.
Swerts S, Van Gasse A, Leysen J, Faber M, Sabato V et al. Allergy to illicit drugs and narcotics. Clinical & Experimental Allergy 2014; 44(3): 307-318. (doi:10.1111/cea.12177)
Editor’s comment: : This comprehensive review focuses on the different classes of drugs that tend to be abused. It reviews allergic reactions to these drugs which include: central nervous system depressants (such as cannabis, opioids and kava), stimulants (cocaine, amphetamines, khat and ephedra), and hallucinogens such as ketamine and nutmeg.