MENU
WORLDALLERGY.ORG
Facebook: World Allergy Organization
Twitter: World Allergy Organization
LinkedIn: World Allergy Organization
Back to Top

Speaker Interviews

K. Frank Austen Mariana Castells Estelle Levetin
Marc Rothenberg Juan Carlos Celedon Dean D. Metcalfe
Martin Blaser Ilan Dalal Joshua Milner
Claus Bachert Erika Jensen-Jarolim Wanda Phipatanakul
Jonathan Bernstein Christine Johnson Avner Reshef
Luis Caraballo Peter Le Souef Margitta Worm

K. Frank Austen, MD, Brigham and Women’s Hospital, Boston, Massachusetts, USA

Read more about Dr. Austen, here

What new findings or insights can attendees look forward to in your session?
We have identified a third receptor for the cysteinyl leukotrienes, GPR99 or CysLT3, that resides in the epithelium of the nose and lung. It is selective for LTE4 and mediates mucin release from the goblet cells. The CysLT3R can be activated by cysLTs from submucosal mast cells in the airways, linking two innate pathways in a tissue response to the allergen, Alternaria.

Attend the Keynote Session of Dr. Austen:
Tuesday, 6 December 2016
8:30 - 9:30
Keynote Lecture: The Mucosal Leukotriene E4 Receptor CysLT3R Regulates Secretion and Responds to the Mast Cell
Recent Publication: Leukotriene E4 elicits respiratory epithelial cell mucin release thought the G-protein-coupled receptor, GPR99


Marc Rothenberg, MD, PhD, Director of the Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Read more about Dr. Rothenberg, here

What new findings or insights can attendees look forward to in your session?
It's a newly described disease (eosinophilic esophagitis) that is emerging into a major health issue for the allergy field. My talk will uncover the basic understanding of the disease’s emergence, the pathogenesis, current treatment and pipeline.

Attend the Keynote Session of Dr. Rothenberg:
Wednesday, 7 December 2016
8:30 - 9:30am
Keynote Lecture: Eosinophilic Esophagitis: A Rising Concern
Recent Publication: Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.


Martin Blaser, MD, Muriel and George Singer Professor of Medicine, Professor of Microbiology, Director, Human Microbiome Program, New York University School of Medicine, New York City, New York, USA

Read more about Dr. Blaser, here

What are you looking forward to at WISC 2016?
I am a microbiologist and a physician specializing in infectious diseases - interacting with scientist and doctors who deal with allergy and its manifestations should be quite interesting.

What new findings or insights can attendees look forward to in your session?
My hypothesis is that the perturbations to the early life microbiome are fueling the current epidemics in allergic disorders.

 

Attend the Keynote Session of Dr. Blaser:
Friday, 9 December 2016
8:30 - 9:30am
Keynote Lecture: Perturbing Early Life Microbiota Development and Its Immunologic Consequences
Recent Publication: Antibiotics, birth mode, and diet shape microbiome maturation during early life.


Claus Bachert, MD, PhD, Professor and Head of Clinics, Department of Oto-Rhino-Laryngology, University of Ghent, Gent, Belgium

Why do you like speaking/attending WAO conferences and congresses?
It keeps me updated on the important issues in our field!

What are you looking forward to at WISC 2016?
Most important, to meet friends and network in a great atmosphere!

What new findings or insights can attendees look forward to in your session?
It turns out that Staphylococcus aureus is an important driver of allergic disease and Type-2 inflammation. We were excited to find a new group of staphylococcal allergens and identified their mode of action!

Attend the Symposium Session of Prof. Bachert:
Tuesday, 6 December 2016
15:30 - 17:00
Symposium: The Microbiome and Airway Diseases
Session: "Allergens and Superallergens: The Immune Proteome of Staphylococcus Aureus"
Recent Publication: Staphylococcus serine protease-like proteins are pacemakers of allergic airway reactions.


Jonathan Bernstein, FACP, CCI, MD, Professor, Division of Allergy and Immunology, Medicine Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA

Why do you like speaking/attending WAO conferences and congresses?
I enjoy speaking and attending the WAO meetings as it affords me the opportunity of exchanging ideas/information to colleagues around the world.  The WAO is an excellent educational forum and has been an invaluable conduit for promoting the specialty of allergy worldwide.

What are you looking forward to at WISC 2016?
I am very excited about the scientific program which consists of highly acclaimed international experts who will be talking about a very broad spectrum of topics pertaining to basic, translational and clinical allergy and immunology.  Attending this year’s meeting in Jerusalem, Israel, a city that is so vibrant, historical and important to all nationalities will be a very special experience for me.

What new findings or insights can attendees look forward to in your session?
My lecture will focus on the most recent advances as well as gaps in understanding the pathogenesis of chronic urticaria.

Attend the Keynote Session of Dr. Bernstein:
Wednesday, 7 December 2016
11:00 – 12:30
Symposium: Practical Approaches for the Management of Chronic Urticaria 
Session: "Mechanisms of Chronic Urticaria: Do We Understand the Whole Landscape?"
Recent Publication: Investigation of patient-specific characteristics associated with treatment outcomes for chronic urticaria.

The diagnosis and management of acute and chronic urticaria: 2014 update.

Urticaria Guidelines: Consensus and Controversies in the European and American Guidelines.


Luis Caraballo, MD, PhD, Professor, Institute for Immunological Research, University of Cartagena, Cartagena, Colombia

Why do you like attending WAO conferences and congresses?
This is a good opportunity to promote WAO and its mission, share the results of our work, getting to know new colleagues and visit such an important city as Jerusalem.

What new findings or insights can attendees look forward to in your session?
Mite and cockroach allergens are the most important perennial sensitizer and risk factors for asthma worldwide. Several of these molecules have been isolated and produced as recombiant proteins. ​

I will focus on the impact of these allergens in tropical countries; their relationships with parasite allergens and the possible platforms for component-resolved diagnosis of allergy. ​

Attend the Symposium Session of Prof. Caraballo:
Tuesday, 6 December 2016
11:00 - 12:30
Symposium: Update in Aeroallergens
Session: "Mite and Cockroach Allergens"
Recent Publication: EAACI Molecular Allergology User’s Guide.

IgE responses to Ascaris and mite tropomyosins are risk factors for asthma.


Mariana Castells, MD, PhD, Associate Physician, Brigham and Women's Hospital, Associate Professor of Medicine, Harvard Medical School, Boston, Massachusetts, USA

Why do you like attending WAO conferences and congresses?
I enjoy the diversity of attendees and the exchanges regarding the various approaches to same diseases

What are you looking forward to at WISC 2016?
The plenary lectures and keynote address are always a highlight and I always learn from them.

What new findings or insights can attendees look forward to in your session?
The new classification of children and adult cutaneous Mastocytosis and their prognostic implications.

Attend the Symposium Session of Dr. Castells:
Tuesday, 6 December 2016
11:00 - 12:30
Symposium: Mast Cell Diseases
Session: "Prognosis and Management of Diseases of Mast Cell Activation and Proliferation"
Recent Publication: Cutaneous Manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology.


Juan Carlos Celedon, MD, DrPH, Chief of Service, Division of Pediatric Pulmonology, Allergy and Immunology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA

Why do you like speaking/attending WAO conferences and congresses?
To learn about state-of-the-art research on asthma and allergic diseases from colleagues around the world.

What are you looking forward to at WISC 2016?
Intellectual exchange and networking with esteemed colleagues.

What new findings or insights can attendees look forward to in your session?
I will present the latest findings from our ongoing research on stress and asthma in children and adults, emphasizing novel discoveries in genetics and epigenetics.

Attend the Symposium Session of Prof. Celedon:
Tuesday, 6 December 2016
11:00 - 12:30
Symposium: Beyond Pharmacotherapy: Role of Lifestyle Modification in Managing Asthma as Human Condition in the Age of Technology and Outcomes
Session: "Genetics and Epigenetics of Stress and Asthma"
Recent Publication: Post-traumatic stress disorder, bronchodilator response and incident asthma in World Trade Center rescue and recovery workers. (In Press)

Gun Violence, African Ancestry, and Asthma: A Case-Control Study in Puerto Rican Children.

Stress and Bronchodilator Response in Children with Asthma.

Depression, Asthma, and Bronchodilator Response in a Nationwide Study of US Adults.


Ilan Dalal, MD, Professor of Pediatrics, Allergy and Clinical Immunology Director, Pediatric Allergy Unit, Service E. Wolfson Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Holon, Israel

Why do you like speaking/attending WAO conferences and congresses?
Many physicians and colleagues are attending these meetings and attractive locations worldwide.

What are you looking forward to at WISC 2016?
I am sure it will be a great meeting scientifically, and also a great opportunity to get together with many colleagues from all over the world.

What new findings or insights can attendees look forward to in your session?
Adding new data and clinical aspects to this new modality of treatment

Attend the Workshop of Prof. Prof. Ilan Dalal:
Tuesday, 6 December 2016
13:30 - 15:00
Workshop: Food Allergy II
Session: “Baked Milk Immunotherapy
Publication Coming Soon: Long term outcomes following baked milk oral immunotherapy for IgE-mediated milk allergy


Erika Jensen-Jarolim, MD, Chair of Comparative Medicine, Messerli Research Institute, Vienna, Austria

Why do you like attending WAO conferences and congresses?
WAO is a globally active platform of allergists where one can get the most current news in allergy. Moreover, as the Co-Editor-in-Chief of WAO Journal, I have a great interest in following the most recent scientific developments in allergy.

What are you looking forward to at WISC 2016?
I anticipate high-end information from colleagues, and I am planning to present on brand new results.

What new findings or insights can attendees look forward to in your session?
Allergy and Cancer are complementary in terms of immune mechanisms - I am chairing an international task force on AllergoOncology that enables scientific exchange among experts in this novel field. 

The impact of tumor immunology has gained tremendous attention recently. In this era of checkpoint inhibitors, anticancer vaccines will likely make a breakthrough in the near future. I will report about the impact of Th2 immune responses, which we know so well in allergy, in malignant tissues. These include innate inflammatory cells, antibodies and lymphocytes, which all interact and shape a Th2-biased microenvironment. Importantly, environmental factors do also contribute to the immunosuppressive environment in cancer. This is novel information for most allergists!

Attend the Workshop of Prof. Erika Jensen-Jarolim:
Tuesday, 6 December 2016
11:00 - 12:30
Workshop: Can Monoclonal Antibodies Really be Useful Weapons in Treating Allergic Diseases as they are in Cancer and Autoimmune Diseases?
Session: “AllergoOncology: The Impact of Allergy in Oncology
Recent Publication: Proof of concept study with a HER-2 mimotope anti-cancer vaccine deduced from a novel AAV-mimotope library platform.

IgE-based Immunotherapy of cancer: challenges and chances.


Christine Johnson PhD, MPH, chair, Department of Public Health Sciences. Henry Ford Hospital and Health System, Detroit, Michigan, USA

Why do you like attending WAO conferences and congresses?
I very much like the international settings and talks from scientists from all over the world. Compared to many other diseases, there are far fewer people engaged in research in this area, so bringing everyone from different countries together is a huge benefit.

What are you looking forward to at WISC 2016?
I am especially interested in talks related to the human and environmental microbiotas. I am also interested in talks related to allergy and asthma phenotypes.

What new findings or insights can attendees look forward to in your session?
We have found in one of our birth cohorts that a certain gut microbiota pattern in 1-month-old infants is related to multi-sensitization at age two years.  Further, a number of environmental and lifestyle risk factors for allergy appear to independently impact the infant's gut microbiota.

Attend the Symposium Session of Prof. Johnson:
Tuesday, 6 December 2016
11:00 - 12:30
Symposium: The Microbiome and Its Role in Health Disease
Session: "Early Life Microbiome Dysbiosis and Development of Allergy"
Recent Publication: Joint effects of pregnancy, sociocultural and environmental factors on early life gut microbiome structure and diversity.


Peter Le Souef, MD, MRCP, FRACP, Head of School/Professor (Asthma Genetics Research),
School of Pediatrics and Child Health, University of Western Australia, Perth, Australia

Why do you like attending WAO conferences and congresses?  
Excellent combination of great talks, great locations and catching up with great colleagues.

What are you looking forward to at WISC 2016? 
Presenting our new findings, hearing the latest research, and seeing old friends in a wonderful city.

What’s hot about the topic you are speaking on?
New therapeutic agents discovered by exploiting detailed knowledge of the immune system are being introduced onto the market and these often have indications that restrict administration to patients in the most common demographic. A strong understanding of the mechanisms by which these agents work will allow clinicians to make effective decisions about who outside these indications will benefit from the new agents.

What new findings or insights can attendees look forward to in your session?
Data on which new “designer” drugs are in development or recently on the market and the indications for their off-label use will be presented.

Attend the Symposium Session of Prof. Le Souef:
Friday, 9 December 2016
11:00 - 12:30
Symposium: Severe Asthma in Children
Session: "When Off-Label Medications could be Perscribed"
Recent Publication: Personalized medicine for bronchial asthma and allergy


Estelle Levetin, PhD, Department Chairperson of Biological Science, Professor of Biological Science, College of Engineering & Natural Sciences, University of Tulsa, Oklahoma, USA

Why do you like speaking/attending WAO conferences and congresses?
I have actually never attended a WAO conference or congress. I have thought that it would be important to go, but I have been unable to attend due to my teaching schedule. I have always believed that meeting and interacting with international colleagues helps us realize that the issues we study apply to patients around the world.

What’s hot about the topic you are speaking on?
DNA analyses of fungi over recent years has resolved many long-standing problems with fungal classification. One insight from the new fungal classification is that specific IgE levels in individuals sensitized to fungi appear to closely match fungal phylogenetic relationships. This may translate into diagnostic and treatment benefits.

What new findings or insights can attendees look forward to in your session?
I will present the current view of fungal classification as it applies to fungi considered important allergens. I will describe levels of exposure to allergenic fungi and also discuss some of the current literature linking exposure to exacerbation of asthma.

Attend the Symposium Session of Dr. Levetin
Wednesday, 7 December 2016
13:30 - 15:00
Symposium: Mold Allergy: Is it Real and What Do We Do About it?
Session: "Fungi: What Are They and What Types of Exposure Do We Have to Them?"
Recent Publication: Taxonomy of Allergenic Fungi


Dean D. Metcalfe, MD, Chief, Laboratory of Allergic Diseases, Chief, MCBS/LAD, National Institute of Allergy and Infectious Diseases (NIAID, NIH), Bethesda, Massachusetts, USA

Why do you like speaking/attending WAO conferences?
It provides an opportunity to interact with scientific colleagues worldwide, exchange ideas and form new research collaborations

What are you looking forward to at WISC 2016?
WISC 2016 is focused on allergy and immunology where there is new and exciting information on diagnosis and treatment to share.

What new findings or insights can attendees look forward to in your session? 
The session will update attendees on revisions to the classification of clonal disorders of mast cells and review the latest in the understanding of pathogenesis and disease management.

Attend the Symposium Session of Dr. Metcalfe:
Tuesday, 6 December 2016
11:00 - 12:30
Symposium: Mast Cell Diseases
Session: "The Many Faces of Mast Cell Clonal Diseases"
Recent Publication: IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3.


Joshua Milner, MD, Chief, Genetics and Pathogenesis of Allergy Section, Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA

What do you like about attending WAO's congresses and conferences?
This is actually my first time. The appeal is an international audience with common interests but diverse professional and academic patients, pursuits, and points of view.

What are you looking forward to at WISC 2016?
Hearing new ideas and cutting-edge data, learning about how a disease is manifest and managed around the world, and meeting new people.

What new findings or insights can attendees look forward to in your session?
We have found a genetic cause for a rather common disorder that allergists likely encounter rather frequently, and in studying these patients have learned a number of new things about an entity often referred to as the mast cell activation disorder. The findings are under review right now.

Attend the Symposium Session of Dr. Milner
Wednesday, 7 December 2016
13:30 - 15:00
Symposium: New and Old Hyper-IgE Syndromes
Session: "A Common Monogenic Cause for the Mast Cell Activation Syndrome"
Recent Publication: Mendelian inheritance of elevated serum tryptase associated with atopy and connective tissue abnormalities.


Wanda Phipatanakul, MD, MS, Associate Professor of Pediatrics, Harvard Medical School, Physician, Division of Immunology Research, Boston Children’s Hospital, Boston, Massachusetts, USA

Why do you like attending WAO conferences and congresses?
Great meeting, international stimulation, meeting up with friends and colleagues around the world, travel to interesting places

What new findings or insights can attendees look forward to in your session?
Disparities and understanding risk factors in inner-cities and ways to decrease these disparities has been hot area of research. I hope to discuss new findings in this area, particularly since my work has focused on schools and communities, where homes had been the focus in the past

Attend the Symposium Session of Dr. Phipatanakul:
Thursday, 8 December 2016
13:30 - 15:00
Symposium: Asthma and Poverty: What Can Be Done?
Session: "Asthma in the Inner Cities of Developed Countries"
Recent Publication: Introducing an environmental assessment and intervention program in inner-city schools.


Avner Reshef, MD, Senior Consultant, Angioedema Center, Allergy & Immunology Unit, Sheba Medical Center, Affiliated to Tel-Aviv University, Ramat Gan, Israel

Why do you like speaking/attending WAO conferences?
WAO's conferences brings people from all around the globe with the main purpose of interacting and exchanging knowledge and experience. It is therefore, a good opportunity to present the 'cutting edge' of research and developments.

What are you looking forward to at WISC 2016?
Hosting the WISC 2016 in Jerusalem sends an important message: science links all professionals across political differences, national diversities and physical boundaries.

What new findings or insights can attendees look forward to in your session?
The role of two central chemical mediators- Histamine and Bradykinin in tissue swelling (Angioedema) has been better clarified over the last 2 decades. My presentation will underscore the differences and similarities between these two systems, its relevance to known clinical entities, and discuss current and future therapeutic approaches.

Attend the Symposium Session of Prof. Reshef:
Tuesday, 6 December 2016
13:30 - 15:00
Symposium: Chronic Urticaria
Session: "Angioedema"
Suggested Publications: Bradykinin and the Pathogenesis of Hereditary Angioedema.

Mast Cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.


Margitta Worm, Prof. Dr. med., Klinik Für Dermatologie, Venerologie Und Allergologie, Charité - Universitätsmedizin Berlin, Berlin, Germany

What do you like about attending WAO's congresses and conferences?
I enjoy the international spirit with the opportunity to meet colleagues working in allergy throughout the world.

What are you looking forward to at WISC 2016?
To gain insight on state of art allergology from different international perspectives.

What new findings or insights can attendees look forward to in your session?
Food induced anaphylaxis has increased the recent decades and the knowledge on risk factors is crucial to better identify those patients with high risk. Data from the European anaphylaxis registry including an assessment of risk factors will be presented. Most relevant risk factors for food induced anaphylaxis are age, mastocytosis and the concomitant intake of certain cardiovascular drugs among others. A novel approach to create a relative risk assessment of these factors will be presented and should help clinicians in clinical practice to better classify patients at risk.

Attend the Symposium Session of Prof. Worm
Wednesday, 7 December 2016
13:30 - 15:00
Symposium: What Really Happens during Food Triggered Anaphylaxis
Session: "Who is at Risk of Food-Triggered Anaphylaxis?"
Recent Publication: Anaphylaxis in children and adolescents: The European Anaphylaxis Registry.

Ramipril and metoprolol intake aggravate human and murine anaphylaxis: evidence for direct mast cell priming.