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National Center for Child Health & Development (Tokyo, Japan)

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The National Center for Child Health and Development (NCCHD) consists of a Children’s Hospital, a Center for Clinical Research, and a Research Institute that conducts basic scientific research. These three facilities cooperate to promote the health and well–being of future generations through both medical care and research, including in the field of allergy. In particular, the NCCHD is designed as the primary facility having as its mission the provision of appropriate medical care to patients with allergic diseases in Japan.

The NCCHD’s Division of Allergy has a reputation for excellent translational and clinical research on such allergic diseases as food allergy, asthma, eosinophilic gastrointestinal disorders (EGID) and atopic dermatitis. Under the direction of Prof. Yukihiro Ohya, the Division of Allergy focuses mainly on development of preventive strategies for allergic diseases and recently published several epoch-making papers in this field (i.e., Natsume O et al. Lancet. 2017;389:276; Horimukai K et al. J Allergy Clin Immunol. 2014;134:824).

The NCCHD’s Department of Allergy and Clinical Immunology has a reputation for excellent basic and translational research in allergy and clinical immunology. Under the direction of Prof. Kenji Matsumoto and Prof. Hirohisa Saito, this Department investigates mainly the mechanisms of allergic diseases and aims to develop new therapeutic strategies for allergic diseases. They have published several important papers in this field (i.e., Takeda T et al. J Allergy Clin Immunol. 2016;138:1395; Shoda T et al. J Allergy Clin Immunol. 2016;138:299; Morita H et al. Immunity. 2015;43:175). Dr. Hideaki Morita focuses on the roles of type 2 innate lymphoid cells in induction of allergic inflammation. Dr. Ichiro Nomura conducts translational research on EGID to clarify the pathogenesis of EGID.

In line with the WAO’s mission to intensify and accelerate multidisciplinary scientific and clinical innovation, these Departments of the NCCHD are working to support educational programs on both translational and basic research.