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Yong Loo Lin School of Medicine - National University of Singapore (Singapore)

Yong Loo Lin School of Medicine, National University of Singapore


The Yong Loo Lin School of Medicine, National University of Singapore (NUS) is the one of the largest academic medical centres in Singapore and the only centre providing centralized paediatric and adult allergy, clinical immunology & rheumatology services in the country.


Our vision is to be a world-class academic centre for clinical care, education and advocacy for children and adults with allergies, immunological and rheumatological disorders.


Clinical Services

The Centre is helmed by academic clinicians who are internationally recognized for their clinical, educational and research expertise in allergy (food allergy, atopic dermatitis, allergic rhinitis), pulmonology, primary immunodeficiency disorders and autoinflammatory disorders. We provide comprehensive diagnostics and therapeutics for adults and children with a broad range of allergic disorders, including food and drug allergy workup and challenges, desensitization, drug, venom and food oral immunotherapy as well as biological therapy.

We are also a major referral centre offering evaluation and treatment of patients with rheumatic diseases for Southeast Asia and beyond, including ultrasound, standard immunosuppressive drugs as well as biologics. We also provide a comprehensive service for the diagnosis and management for all common and complex respiratory and sleep disorders in infants, children and teenagers.



We are internationally recognized for our leadership in childhood allergy, asthma and immunology research. Our academic clinicians are key investigators in several birth and preconception cohorts in Singapore: GUSTO (Growing Up in Singapore Towards Healthy Outcomes) birth cohort, S-PRESTO (Singapore Preconception Study of Long-Term Maternal and Child Outcomes) preconception cohort, and the Nutritional Intervention Preconception and during Pregnancy to maintain healthy glucose levels and offspring health (NiPPeR) cohort studies. These are the some of the largest birth cohorts in Asia, and one of the very few preconception cohorts in the world.

Our research expertise is in Atopic Dermatitis (AD), Asthma, Allergic Rhinitis and Food Allergy Epidemiology unique to Asia. We also aim to develop novel approaches for AD and Food Allergy treatment and prevention, and harnessing bioengineering and bioinformatics approaches towards developing biotherapeutic interventions. We are affiliated with the National AD network and the Asian Skin Microbiome Programme (ASMP), which aims to generate new functional understanding of the skin microbiome in relation to skin health and inflammation for the development of translatable clinical interventions.

Our centre collaborates with key leading research institutions and organizations around the world, such as the Murdoch Children’s Research Institute (MCRI), World Allergy Organization (WAO), European Academy of Allergy and Clinical Immunology (EAACI) and the American Academy of Allergy, Asthma & Immunology (AAAAI), the Asia Pacific Academy of Pediatric Allergy, Respirology and Immunology (APAPARI) and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). We are also key members of international consortia such as the APAPARI Anaphylaxis Registry, WAO Allergy Prevention Workgroup and the Global Food Allergy Epidemiology Network.



We are the largest tertiary academic centre in Singapore catering to paediatric and adult allergy, immunology, rheumatology and pulmonary education. We have trained medical, dental, science and pharmacy undergraduates as well as basic science postgraduates and basic and subspecialty clinician trainees and regularly receive overseas clinical fellows for year-long clinical fellowships. Our trainees also have the opportunity to rotate to various subspecialties closely related to allergy, such as Respiratory Medicine, Dermatology and ENT, providing a comprehensive and holistic training experience across multiple disciplines. We work closely with allied health partners, including Nursing, Dietetics and Pharmacy, with an interest in allergic diseases to allow them to practice at the top of their license in the realm of allergic diseases, under close supervision by a specialist. We are also actively engaged in education efforts with other clinicians in the region, particularly in low-resource countries in South-East Asia.



The center is actively engaged in advocacy for our patients through hosting of community education programs for doctors, nurses and lay public, as well as international conferences to share expertise with clinicians in the region. We also provide training programmes for school teachers and caregivers in the recognition and management of allergic and rheumatological disorders to enhance quality of care for our patients.

We work closely with national government agencies, including the Health Sciences Authority and the Academy of Medicine in national surveillance strategies for drug allergies and various clinical practice recommendations for a range of allergic conditions. 


Dr. Elizabeth Tham Dr. Amelia Santosa
Co-Director Co-Director

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