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Children’s Hospital of Philadelphia & Penn Medicine (Philadelphia, United States)

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Children’s Hospital of Philadelphia &
The Hospital of the University of Pennsylvania

The Division of Allergy and Immunology at Children’s Hospital of Philadelphia (CHOP) provides comprehensive evaluation and treatment of allergic diseases and asthma. We are one of the largest pediatric allergy groups in the region and care for patients from the Philadelphia area and around the world. The Division sees patients with all aspects of allergic and immunologic issues including food allergy, atopic dermatitis, allergic rhinitis, eosinophilic esophagitis, hypereosinophilic syndrome, mast cell disorders, drug allergy, asthma, hereditary angioedema, all types of primary and secondary immune deficiencies. The Division has active clinical, translational and basic research in atopic dermatitis, food allergy, eosinophilic esophagitis, primary immune deficiencies and drug allergy. The Division also collaborates with clinical teams from across the hospital, including the Division of Gastroenterology and Nutrition for Eosinophilic Gastrointestinal Disease, Early Onset Inflammatory Bowel Disease, Integrative Medicine and Food Protein Induced Enterocolitis, Pulmonary Medicine for severe asthma, Dermatology for Severe Atopic Dermatitis, Oncology for Bone Marrow Transplant for Primary Immune Deficiency.

CHOP is committed to researching and finding cures for chronic and fatal pediatric illnesses. Our physician-researchers draw on the latest available information about the human genome to customize therapies to variations in genetic makeup. CHOP has more than $329-million in federal funding and 800,000 sq. ft. of space devoted to research.

Penn Medicine’s section of Allergy and Immunology, part of the Division of Pulmonary, Critical Care and Allergy and Immunology in the Perelman School of Medicine at the University of Pennsylvania, provides comprehensive and compassionate care of patients with a broad spectrum of allergic and immunologic disorders.  Collaborative relationships with multiple divisions of Penn’s Department of Medicine include: GI for evaluation of EoE, EGID and GI presentations of mastocytosis; pulmonary for evaluation of complex asthmatic patients with overlap syndrome with COPD as well as evaluation of ILD, sarcoidosis, cystic fibrosis and pulmonary hypertension; rheumatology for the evaluation of EGPA and autoimmune disorders; dermatology for evaluation of cutaneous drug allergies, contact dermatitis, vasculitis and dermatologic expressions of connective tissue diseases; medical genetics for assessment of genetic evaluation of immunologic disorders such as Hyper IgE Syndrome and chronic granulomatous disease; hematology/oncology for evaluation of mastocytosis, lymphopenia and monoclonal disorders; and cardiology for evaluation of cardiac manifestations of hypereosinophilia syndrome.

Research areas in Penn’s Section of Allergy have included drug allergies, asthma and health care disparities. Over the past 30 years, Penn physicians and scientists have participated in many important discoveries, including: the first general vaccine against pneumonia, the introduction of total intravenous feeding, the development of magnetic resonance imaging (MRI) and other imaging technologies and the discovery of the Philadelphia chromosome, which revolutionized cancer research by making the connection between genetic abnormalities and cancer. With more than $900 million in annual R&D expenditures, Penn is one of the nation's top research universities, not only generating important new knowledge in the fields of medicine, technology, business, science, and beyond, but applying this knowledge to improve the lives of individuals and communities at home and around the world.

CHOP was founded in 1855 as the nation’s first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals, and pioneering major research initiatives, Children’s Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country. In addition, its unique family-centered care and public service programs have brought the 546-bed hospital recognition as a leading advocate for children and adolescents.

The Perelman School of Medicine is the oldest medical school in the United States. Penn is rich in tradition and consistently at the forefront of new developments and innovations in medical education and research. The University of Pennsylvania opened its School of Medicine, the nation’s first, in 1765. The mission of Penn Medicine is to advance knowledge and improve health through research, patient care, and the education of trainees in an inclusive culture that embraces diversity, fosters innovation, stimulates critical thinking, supports lifelong learning, and sustains our legacy of excellence.

CHOP is the teaching facility of the University of Pennsylvania. There are separate but adjacent structures. Most faculty members of CHOP are faculty members in the department of Pediatric in the Perelman School of Medicine.